Thursday, February 26, 2009

Job Oppurtunities With Department Of Biotechnology

Related Website : www.dbtindia.nic.in
Last Date Of Applying Through Application : 1st,April 2009
Source : The Hindu

Wednesday, February 25, 2009

National Workshop on Computational Chemistry & ChemoinformaticsApproaches in Modern Drug Discovery

======================================
National Workshop on Computational Chemistry & ChemoinformaticsApproaches in Modern Drug Discovery
Venue: IIITM-K, Nila Building, Technopark, trivandrum
Dates:18 - 21 March, 2009
The sessions in the workshop are handled by Dr. K. A. Prince Xavierand Dr. T. K. Manojkumar. Both the faculties finished their Ph. D. inComputational Chemistry and have a good experience in the applicationsof different computational techniques in Computational Biology andDrug Discovery.
TopicsForce field and Molecular MechanicsChemoinformatics : Drug databases : Tools to accelerate hitand lead identificationTarget Identification and ValidationDrugability index of protein targetsPreparation of protein targets for molecular dockingChemogenomics (Chemical genomics) approaches in target identificationProtein ligand dockingProtein homology modelingVirtual library generationIn-silico screening / Docking of ligandsPrediction of binding modesIn-silico ADME/Tox properties predictionEstablishing quantitative structure-activity relationship (QSAR) &structure-property relationship(QSPR)Receptor-based and ligand-based pharmacophore designFragment-based drug designDesign of focused, diverse and thematic chemistry librariesLead optimization & de-novo designCalculation of physico-chemical properties

Biological and physico-chemical predictive model buildingBiosimulationHands on training using molecular modeling, visualization and docking tools
Faculty, students, teachers from educational institutions andprofessionals from industry are welcome to attend the workshop. Thenumber of seats is limited to 40.
Registration fee for people from academics is Rs. 3,500/- and thosefrom industry are Rs. 10,000/-. For PG students, the registration feewill be Rs. 2,500/-. Registration fee can be paid in the form ofDemand Draft in favor of "Director, IIITM-K" payable at anynationalized bank in Trivandrum. For registering for the workshop,participants are requested to send a letter specifying your name,official address along with DD to
Dr. T. K. Manojkumar,Park Center, Indian Institute of Information Technology and Management – Kerala,Technopark Campus, TrivandrumKerala – 695 581E-mail: manojtk@iiitmk.ac.inPhone: 09995482821Office: 0471-2700777
Last Date of Registration: 10th March, 2009

Research : In Frontier Areas Of Biotechnology And Applied Biology



Source : The Hindu

Thursday, February 19, 2009

One Day Workshop on Clinical Trial Research and Data Management


Bioinformatics Institute of India has been organized workshop for the students and professionals of Medical Science, Pharmacy, and Biotechnology. The goal of this organized workshop, to enhance the knowledge in field of Clinical trial research and data management, to understand the problem of medical science and optimized them by using the heuristics methods of Clinical Research. The major focusing areas of the workshops are:

• Clinical Trial Research and its Applications
• Clinical Data Analysis and management
• Good Clinical Practices
• Pharmacovigilance
• Medical Writing and Documentation

The honorable, Chief and leading person of the workshop are Dr. Kumud Sarin (Program Director BII) Dr. Neena Valecha (Deputy Director of MRC),Mr.Asif (IFFCO-Tokyo).Their crucial information and interesting lectures on highlighted area of clinical trial will surely make it easy to understand the recent scenario of Clinical Research & Data management in Medical Science.

Registration Fee* 600\-Rs

Registration fee payable by DD/Cheque in favour of “Bioinformatics Institute of India” payable at Delhi/New Delhi.

Last date for registration: February 28, 2009.

Date: 07\03\2009
Time: 9.30 am to 5.30 pm
Venue: Bioinformatics Institute of India
C-56A\28, Sec 62, Noida, U.P

For any further information, contact:

Program Director

Dr. Kumud Sarin

Bioinformatics Institute of India
C-56A\28,Sec 62,Noida
e-mail: kumud@bii.in
Phone No: 0120-4320801\02
9810535368,9818473366

Wednesday, February 18, 2009


Source : The Economic Times

Sunday, February 15, 2009

“Bioinformatics and Its Emerging Industrial Applications” - Workshop at IIT Delhi

One day
Workshop on

on

“Bioinformatics and Its Emerging Industrial Applications”




February 28, 2009

at

IIT Delhi





Under the Aegis of




Foundation for Innovation & Technology Transfer,
(FITT), IIT Delhi



Scope and Objectives

Recent advances in bioinformatics and the significant increase in the computational powers in the form of super computers have made it possible to utilize the genetic data base (data mining) which has been collected so far. In fact, the success of genome sequencing efforts and bioinformatics resulted in a vast amount of data over the last two decades. The number of genetic sequences in the Gen Bank gene sequence repository of the National Center for Biotechnology Information (NCBI) has increased tremendously over the last two decades. Bioinformatics has to use this mountain of data with the help of super computers in the efforts. Gene mining for understanding life and developing absolute cures for life threatening diseases. The task of the bioinformations is to demonstrate how in-silico simulations facilitates experiments in the laboratory, towards personalized medicine (individual specific drugs with no side effects). Health informatics is another tool which may act as a big aid in this direction. Bioinformatics may have applications not only in pharmaceutical industries but in several other industries.

In fact, significant improvements in the studies of genomics and proteomics, and concurrent progress in X-ray crystallography, nuclear magnetic resonance techniques along with bioinformations have given rise to expectations that the three dimensional structure or reliable homology modeling can be achieved in a reasonably short time. Mapping of the human genome seems to be nearing completion. Chemoinformatics and chemogenomics help in the bioinformatics studies. There is a need to take steps to decipher the language of DNA from an energetic perspective. Metabolic pathway analysis of complete genome sequences enables identification of all members of essential pathways that are present as well as genes that are missing from the potential pathogens. Chemoinformatics and structural genomics would provide substantial knowledge about the increasing number of drug targets. This would trigger the demand for the design and new specific inhibitors or ligands tailored to a particular target. Potential drug targets may be identified through metabolic pathway analysis and choke point analysis.

Molecular modeling and modular dynamics simulations help in revealing the primary and secondary structures of different proteins, with their active sites and folds. Homology or comparative modeling uses experimentally determined protein (3D) structural template to predict the conformation of another protein that has similar amino acid sequence. Homology modeling involves generally 4 steps fold assignment, sequence alignment, model building and model refinement. The sequence of database of proteins with known structures (e.g., PDB- sequence database) is searched with target protein and a protein of known 3 D-structure, the two protein sequences are aligned to identify the optimum correlation between the residences in the template and target sequences. The model of the target protein is constructed and checked with regard to conformational aspects and is corrected or energy minimized using force-field approaches. The use of Pro-check helps in ascertaining the protein structure.

Nanodrugs may cross blood-brain barriers to provide or afford drugs for brain tumours, e.g., curcumin, or other nano-sized compounds Drug development is a very laborious, time consuming, costly, energy intensive, difficult and lengthy process. This job is very tedious and involves even trial and error by using a myriad of different chemical compounds. Bioinformatics approach to perform such a gigantic operation of designing and testing so many molecules by docking (AUTODOCK 3.0) to pathogenic proteins makes the job of drug designing easier. Microarrays are gaining importance in bioinformatics and may add to the acceleration of efforts towards drug designing and drug discovery.
The emergence of multiple drug resistance to human pathogens has necessitated the research for newer molecules or compounds from other antimicrobial substances or other sources. Traditionally, the use of medicinal plants for the treatment of human diseases is well known practice in Ayurvedic, Unani, traditional, focal or Homoeopathic, siddha products, naturopathy, food supplements, functional foods, herbs, etc. systems of medicines. The medicinal plants and other natural product sources have provided leads for antiparastic, antiviral, antifungal, antibacterial, anticancer etc. diseases. Such natural products include flavonoids, flavonolignans, lignanoids, terpenoids, coumarins, aurones, naphthoquinones, alkaloids, steroids, quinolines, thiols, phospholipids etc. . Either active principles like curcumin or a group of compounds have made a drug after pharmacodynamico studies. The organic chemical structures of a myriad number of natural products have been identified and their quantitative structure-activity relationship (QSAR) has been studied. Chemoinformatics may help in finding newer drugs including nanodrugs or ligands. Chemists may modify the chemical structure of compounds to design a newer drug molecule for docking. Its toxicity may be tested subsequently. Combinatorial chemistry may help in the synthesis of a series of possible compounds for docking studies. Thus, bioinformatics may help in generating a large array of potential drug molecules on a hierarchy of molecules which may be tested experimentally in the laboratory. However, bioinformatics may help in reducing the gigantic job to a routine and simple job. Nanobiotechnolgy may also open newer avenues in drug discovery.

Bioinformatics does not help only in drug discovery but this also has several other applications in energy, food, chemical fermentation or other industries. In fact, enzyme production and identification of potential microbes for the different biochemical actions is also a very labour and energy intensive, lengthy, costly and tedious job. Bioinformatics can help in revealing the potential microorganisms which may be selected for studies for the production of active enzymes in good yields by using BLAST, gene and protein data banks. The examples include e.g., in energy industries i.e, the discovery of potential microbes for use in hydrogen, biodiesel , ethanol, lipase enzyme production, chiral separations, or for biorefining of fossil fuels. Similar uses of bioinformatics in food and fermentation or chemical industries may be found through gene data mining or nanotechnology.

It is certain that success of future bioinformatics would hinge upon high-performing super computers in developing further computational biology. The role of chemoinformatics, chemistry of natural products, synthetic organic chemistry, artificial intelligence or robotics in this field may not be under emphasized, e.g. the use of artificial neural network in the studies of the function of brain and its networking. Bioinformatics may have great applications not only in pharmaceutical industries but in other industries such as fuel or energy, food, chemical, fermentation and bioengineering or nanobiotechnology based industries. Future would see a huge broadening of horizon of application of bioinformatics in several industries and not just limited to drug industries only e.g., searching suitable microbes for DNA, specialized enzymes, DNA motors etc.

The key driving force for the present day in silicon drug design endeavors are the availability of structural information of targets, emergence of reliable energy functions, discovery and designing of newer molecules and their multiple derivatisation for docking and availability of high end super computers. Bioinformatics may open a new era of therapeutics research which will reduce the time, cost and labour in drug discovery. This way also help the scientists to design better and more efficient chemical trials. Automated drug design in silico seems a reliable dream in the near future where nanobiotechnology may also open newer avanues never seen before.

The following topics would be covered:
1. Computational Biology and Drug Discovery
2. Drug Designing
3. Protein Modeling
4. Genetic Mining and Molecular Bioinformatics
5. Chemical Molecular Modeling and Designing
6. Medicinal Chemistry and Combinatorial Chemistry
7. Chemistry of Natural Products and Drug Designing – QSAR
8. Leads from Alternate Systems of Medicines
9. Microarrays
10. Other Applications of Bioinformatics in Biological H¬¬2 production, Biodiesel, Bioethanol, Biomethane production, Enzyme Engineering, Fermentation, Chemical, Food etc. Industries
11. Chemoinformatics
12. Nanobiotechnology and Nano drugs
13. Health informaics
14. Bioenergatics and Bioinformatics
15. Future Scope


Speakers

Prof. D. K. Sharma, Centre for Energy Studies, IIT Delhi
Prof. B. Jayaram, Head, Chemistry Department, IIT Delhi and
Prof. Saroj Mishra, Former Head, Biochemical Engineering and Biotechnology Departments, IIT Delhi and other Speakers from Outside.

METHODOLOGY:

Lectures and Discussions

WHO SHOULD ATTEND:

Engineers, Scientists, Managers and Other Executives working in the areas of medicines, biotechnology energy, oil refineries, fuel technology, chemical technology, fermentation, food, enzyme engineering etc.

Registration Fee* After Dec. 15, 2008 Before or on Dec. 15, 2008

- Students Rs. 2500/- Rs. 2000/-
- Scientists from academic institutes
and R&D organizations Rs. 4500/- Rs. 3600/-
- Industries Rs. 5000/- Rs. 3600/-

• There will be 20% (early bird) concession in the registration fee for the participants who register before December 15, 2008

Registration fee payable by DD/Cheque (Delhi A/c) in favour of “FITT, IIT Delhi”

Last date for registration: February 16, 2009

DATES AND VENUE:

Date: February 28, 2009
Venue: Centre for Energy Studies, IIT Delhi

ACCOMMODATION

This is a non-residential programme. The participants are expected to make their own arrangements for stay. Subject to availability, the organizers will try to book accommodation on payment basis within the guest houses of IIT Delhi, if requested sufficiently in advance through the Registration Form.



For any further information, contact:
Coordinator
Prof. D.K. Sharma
Centre for Energy Studies
Indian Institute of Technology, Delhi
Hauz Khas, New Delhi – 110 016
Tel : 2659 1256, Mob: 9818227168
e-mail: sharmadk@ces.iitd.ernet.in


REGISTRATION FORM

One day Workshop on
Bioinformatics and Its Emerging Industrial Applications
(February 28, 2009)

Name Dr/Mr/Ms .:_____________________________________________

Designation :______________________________________________

Organization :______________________________________________

Address :_____________________________________________

_______________________________________________

Email: ________________________________

Phone: _______________________________

Fax: _________________________________

Fees Payable to “FITT, IIT Delhi” Draft/Cheque No.: __________________________

Dated: ________________________________ Drawn on : (Bank)__________________________

Rs. __________________________________


Signature of applicant





Please send your registrations to:
Mr. K.K.Roy
Manager (Tech./Admn.)
Foundation for Innovation and Technology Transfer (FITT)
Indian Institute of Technology Delhi (IITD)
Hauz Khas, New Delhi-110016
Phone : 011-2659 7285, 2659 7164
Fax: 011-2685 1169
Email: krityroy@yahoo.com
uttamaswal@hotmail.com

Friday, February 13, 2009

One Day Workshop on Bioinformatics Conducted At BII

BII Conducted One Day Workshop On Bioinformatics on 7th Feb’09 .The workshop provided an overview of Bioinformatics and computational approaches useful in analyzing complex biological system to provide solutions to biological problems.The workshop was meant for all the life sciences students offering them hands on exposure of bioinformatics and 25 students have participated in the workshop.

Dr.Sridhar Sivasubbhu from IGIB, guest faculty at BII had given lecture on “Genome Annotation & Bioinformatics”. Dr. Kumud Sarin Senior Program Director BII had given lectures on “Bioinformatics – Concept and Application” and “Application of Bioinformatics in Drug Designing . Mr. Arvind and Ms.Priti have taken Practical sessions.The session was concluded by Workshop Certificate's distribution.

Participant’s Profile

Academicians,Graduates&PostGraduates in Life Science, Bioinformatics Students & Professionals, Professors, Researchers, Professionals from Industry

Following topics were included for workshop

Bioinformatics: Concepts and Applications, Biological databases, Bioinformatics Soft wares, Emerging Dimensions of Bioinformatics, Computational Analysis of Biological Data, Data Mining Application of Bioinformatics in Drug Designing

List of Appeared Candidates in Work Shop :

Participants NameAcademic QualificationFrom College's\University
Amit Kumar Dubey M.Sc Chemistry (Lect. )Dr.G.S.P.G College,Varanasi
Anirban Chakraborty B.Sc Microbiology Delhi University
Charvi Hasija B.Sc MicrobiologyDelhi University
Geetanjali Bisht B.Sc MicrobiologyDelhi University
Hoor Fatima B.Sc Bioinformatics’Delhi University
Jyotsana Pandey B.Sc BioinformaticsC.C.S.Univ Meerut
Kaveri VermaM.Sc Bioinformatics
Manvi Gupta B.Sc MicrobiologyDelhi University
Neha Goel M.Sc BiotechnologyC.C.S.Univ Meerut
Neelkamal M.Sc Bioinformatics C.C.S.Univ Meerut
Parul Sehgal B.Sc MicrobiologyDelhi University
Suchita Panda B.Sc MicrobiologyDelhi University
Shalu Tyagi M.Sc BioinformaticsBanasthali University,Jaipur
Sandhya Tyagi M.Sc BioinformaticsBanasthali University,Jaipur
Udayveer Singh Yadav B.Sc BiotechnologyS.G.I.Greater Noida
Vivek Kumar Singh B.Sc BiotechnologyS.G.I.Greater Noida
Zehan B.Sc BiotechnologyS.G.I.Greater Noida
Deepti Puneet Srivastava M.Sc BiotechnologyBangalore University
Piyush Prakash Singh M.D(Psychology)A.M Univ ,Aligarh

Monday, February 9, 2009

BII Introduced a New "Industry Program In Forensic Science"

Program Overview :
BII is introducing a new 12 months Industry program in forensic sciences.The program qualifies students to apply their knowledge of science to the investigation of crime,keeping in mind the prospective students and for professionals who are well versed.
The program targets those who are already working in crime laboratories, medical examiner’s offices, and the like, and who already have an undergraduate degree and several years of experience in the field. Because they don’t need practical training in most cases, they are interested in gaining theoretical knowledge to enhance their career and job prospects.
Benefits :
One should be fully aware that what to expect from this field since Since it is a matter of a future line of work. A forensic scientists has more than doubly increased in cracking crime cases of today. Since the crime detection methods have become far more advanced the police are in need of the services of forensic scientist to help them with criminal cases.
Job Prospects and Career options :
One can find employment in India with :-

Law enforcement agencies
Police
Legal system
Investigative services of the government and also private agencies.
Teachers in institutes that conduct courses in this subject

One can find employment in foreign countries with.The foreign land job prospectus includes working as

A medical examiner
Crime scene examiner
Crime laboratory analyst
Forensic engineer.
Forensic scientists also work to produce psychological profiles of the causes, methods and consequences of crimes

Course Content

Below mentioned Modules have a series of learning objectives and an assignment that typically requires the student to research a topic, write a brief report. This allows for students to work on assignments at the times that are most convenient for them, yet they are kept on track by the deadlines for submission.

§ Module 1: Introduction to Forensic sciences
§ Module 2 : Forensic medicine and Medico-legal Aspects
§ Module 3 : Biological Anthrapology
§ Module 4 : Forensic Toxicology
§ Module 5 : Forensic Serology
§ Module 6 : Introduction to criminology
§ Module 7 : Documentation and Forensic analysis of biological evidence
§ Module 8 : Computer Forensic

Must Join

Typical students work in crime laboratories or related fields. The program also attracts crime scene investigators, detectives, and attorneys; they tend to take only a few courses to enhance their knowledge base. Also, students who work in pharmaceutical, clinical, and environmental laboratories and are looking for a career change.

Wednesday, February 4, 2009

Distance Learning Proves Lucrative

Distance education Institutes pursue continuing education in areas such as regulatory affairs make the industry stronger by sharing their knowledge with clients,peers and professionals who are intended to make a career in the area of regulatory affair.Distance or Certification program are mostly designed to elevate professional standards, distinguish individuals demonstrating knowledge essential to regulatory affairs, and enhance individual performance.

Distance programs such as regulatory affair program gives a complete insight or industrial focus regarding hierarchal profiles,dealing with regulatory related submission and filling before government agencies,putting faster working trends so as to avoid delay in drug discovery subsequently making pharmacovigilance successful thereby claiming a drug to be safe,effective,pure with appropriate strength in the interest of public and national health,to improve one’s efficiency and performance in an organized structure.

Distance education focuses on providing comprehensive and significant knowledge Distance program are intended to provide professionals with a clear picture of a corporate world,program like regulatory affairs are usually designed keeping in mind the current developments targeting working professionals regarding the latest industrial policies their requirements,enabling them to employ their knowledge according to current industrial profiles.
Professionals who are well versed wtih current industrial trendz,meeting deadlines,work pressure,delivering projects on time.Distance education act as a catalyst for their career where they can learn to enhance their capabillities,skills,strengths and can improve attitude towards company's goal

Distance program can prove lucrative for professionals who are working and for those who thought of switching it as a career. Infact,these program are designed keeping in mind for the professionals who are already absorbed by pharma and biotech companies especially for various in house regulatory activities or may be associated with other projects and departments.
For Industry Program In Pharma Regulatory Affairs Click here http://www.bii.in/pharma/pharma_regulatory_prospectus.asp

Job Opening in Rajiv Gandhi Centre for Biotechnology

Monday, February 2, 2009

Offshoring Creates Regulatory Oppurtunities

The offshoring business majorly from US and UK of Regulatory approvals for pharmaceuticals,medical devices,diagnostics is flourishing and gearing up for revenue generation in India.As international authorities and organizations are reviving up the rules and regulations, shortly announce to establish special facilities and labs consequently creating more job opportunities for professionals in diverse area.

Organizations from developed countries are giving opportunities to big companies based in India.Few Big companies should comply and adhere to international standards for better opportunities.Numerous Indian MNCs are in revenue sharing alliance with US and UK based organizations. Moreover many Indian companies are revealing that the outsourcing revenue will generate a 60% revenue increase in the coming two years as compared to present 20% revenue generation.

Apart from tougher regulation in US,UK is also a comparatively tougher market due to various regulations. In order to clear through these regulatory hurdles foreign companies have now outsourced all the regulatory relevant tasks including filling,post marketing,surveillance,regulatory related in house activities which includes documentation.These offshore activities will generate more jobs in the regulatory sector in India.

As India is creating more and more opportunities in off shoring sectors,many professionals are heading towards the same sector.Professionals with sound background,well versed can get a break and can excel in the sector.Moreover myriad IT majors who are already made a mark into software offshoring bringing their new facilities where they will carry out all the regulatory related offshoring activities and companies are searching high for talent

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