Register for BINC Exam Till 24 December 2007

Details are available at : http://203.129.231.23:8080/binc/

Application: 31 August 2007 Deadline: 24 December 2007 Examination: 16-17 February 2008
"BINC registration is ON"
BioInformatics National Certification (BINC) Examination will be conducted on 16-17 February 2008. The Department of Biotechnology (DBT), Government of India has instituted this examination with an objective to certify Bioinformatics professionals and to facilitate industries and potential employers for recruitment. University of Pune has been identified as a nodal agency by the Department of Biotechnology, Govt. of India to coordinate this examination along with five centres namely, Jawaharlal Nehru University, New Delhi; Anna University, Chennai; West Bengal University of Technology, Kolkata and Institute of Bioinformatics and Applied Biotechnology, Bangalore.
Last year number of candidates appeared were 475 and 8 candidates got certified. They also received cash award of Rs.10,000/-. DBT has also agreed to fund scholarship(JRF) to top 10 candidates if they join any Indian academia or research institute for Ph.D. in the field of Bioinformatics or computational biology.
“It is a privilege and an honor to be the coordinator of the BINC examination. It is just not a responsibility but a commitment to make a difference. I request the media and the students alike to publicize the BINC exam so that both, the bioinformatics students and the potential employers, benefit from this certification at the national level.”
The Coordinator BINC


BINC Syllbus

Details at: http://203.129.231.23:8080/binc/syllabus.html

BiologyCell Biology & GeneticsBasic:
Basic aspects of Prokaryotic and eukaryotic cells; membranes and cellular compartments, cell organelles, structure and function
Cell motility and shape: cytoskeletal elements, cilia and flagella; motor proteins.
Cell-cell interactions and signal transduction: Intercellular junctions, signaling by hormones and neurotransmitters.
Cell cycle and its regulation; events during mitosis and meiosis
Mendelian principles of inheritance, sex linked inheritance.
Concept of linkage, linkage maps and recombination.
Mutations – molecular, gene/point and chromosomal types and molecular basis.
Phenotype and genotype relationships, role of environment, from gene to phenotype, gene interactions. Study of quantitative traits.
Genetics of populations, genetics and evolution.
Concepts of generation of diversity and specificity in immune system Immunological methods. Advanced:
Vesicular transport and protein traffic in cells.
Inherited disorders.
Second messenger, different mechanism of signal transduction, concepts in signal network, molecules involved in various signaling pathways such as G-proteins, receptors, proteins kinases, calcium binding proteins.
X linked Vectors, autosomal diseases, mitochondrial related disease, QTLS methods for diagnostics.
Extra chromosomal inheritance
Immune response.
Genetics and diseases.
Extra chromosomal inheritance. Molecular BiologyBasic:
Prokaryotic genome organization and structure.
Prokaryotic gene expression, operons – positive & negative regulation, factors involved in gene regulation.
Eukaryotic genome organization and structure, Mechanism of gene expression in Eukaryotes, promoter & regulatory sequences, basic, mechanism of transcription and transcriptional activation, role of transcription factor.
Mechanisms by which genome undergoes changes, recombination, mutation, inversion, duplication, transposition.
Basic mechanisms involved in translation & transcriptional regulation. Advanced:
Genome organization, Initiation, elongation and termination of transcription – template & enzyme properties.
Methods for studying gene expression and regulatory sequences, large-scale expression analysis, use of microarrays.
Genetic information transfer, details of regulation in eukaryotes & prokaryotes, horizontal gene transfer.
Processing of RNA and Proteins - Transport and Stability
Organization of eukaryotic genome. Methods for studying variation and polymorphism at genome level, RFLP, Fingerprinting, RAPDs.
Epigenetic mechanisms of inheritance and regulatory RNA molecules. Biochemistry Basic:
Carbohydrates and lipids, their importance in cells.
Proteins: Amino acids and peptides; primary, secondary, tertiary and quaternary structures.
Nucleic acids: Bases, nucleotides, RNA and DNA. Different structural form of DNA, denaturation and renaturation of DNA.
Enzymes: Units of activity, coenzymes and metal cofactors, temperature and pH effects, Michaelis-Menten kinetics, inhibitors and activators, active site and mechanism of enzyme action, ribozyme and abzymes.
Carbohydrate metabolism: Glycolysis, gluconeogenesis, glycogenolysis, glycogenesis ,TCA cycle and oxidative phosphorylation. Advanced:
Concept of biochemical regulation, feed back and feed forward systems, biochemical oscillations, Transport mechanisms
Molecular mechanisms of small and large molecules including ions, regulation of protein pathways
Isoenzymes, allosteric enzymes, regulation by covalent modification.
Concept of metabolic pathways, Organization of metabolic systems: enzyme chains, multienzyme complexes and multifunctional enzymes, regulatory enzymes and feedback control of metabolic pathways.