1-2 months Project
Project-I
We’ll consider the human genome.
Scan the human genome for at least 5 putative genes.
Apply different bioinformatics tools.
The gene which gives the best or interesting result, select it.
Further gene analysis can be carried out using several other tools.
Project-II
1. The members of a protein family have regions that are shared by many of them
and other regions that show high variability.
1. Choose a family of proteins.
2. Compare several family members (at least 20).
3. Give possible explanations for the regions of conservation /variability.
6 months Project
Project I
1. Consider any one biochemical pathways present in a wide range of organisms for example -glycolysis (the degradation of glucose into to create energy (ATP)).
2. Choose a pathway that is shared by at least 3 different organisms.
3. Check which parts of the pathway are shared, and the degree of similarity between the shared components.
4. Explain why some parts of the pathway are shared while others are not.
5. Try to correlate between the degree of similarity of the pathways and the evolutionary distance between the organisms.
6. Pathway distance used to understand phylogeny.
Project-II
1. Search the variants of Lipocalin family.
2. Use the Bioinformatics tools to search the domains and their family.
3. Find the similarity between the domains.
4. Retrieve the structures of these variants using various databases.
5. Find the structural similarity between the domains
6. Protein analysis
7. Check for the pathogenecity of the variants with the help of web tools.
Project-III
1. Consider the TCA cycle of Arabidopsis Thaliana and Oryza Sativa.
2. Study the enzymes involved along with the pathway.
3. Extract the genes.
4. Perform a similarity search among the genes.
5. Find the critical enzyme from the above analysis.
Project-IV
1. Consider the cell cycle of Maccaca mulata and Homo sapiens.
2. Study the genes involved in cell cycle pathway.
3. Find out the function of missing genes with the help of databases.
4. Make the comparative analysis.
Project-V
1. Disese identification
2. Target identification
3. Validation
4. Active site analysis
5. Novel hits compound selection
6. Docking: a) Select target b)design new ligand inhibitor
7. New drug hits
By- BII Training & Project team
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5 comments:
I am student of BSc(Medical Biotech) at Amity Uni. Noida.As per req.of course,I have to undertake 2 months Summer Training(2nd week of June to 1st week of Aug).Do yr program fit to my req?If yes,Kindly send me details for same
i m an msc student frm kerala.i m searching for a project i m interested in your - monyh project.please send me the details to sarathharipad@gmail.com
I am student of M.Sc.BIOINFORMATICS(3rd sem) of BANASTHALI UNIVERSITY.As per req.of course,I have to undertake 6 months project(jan-june ).please send me details.
I am student of M.Sc.BIOINFORMATICS(3rd sem) of Sri Ramakrishna College.As per req.of course,I have to undertake 6 months project(jan-june ).please send me details to shalu_2311@yahoo.co.in.
hello/sir or mam,
I am student of M.Sc. bioinformatics 1st sem of Banasthali University. I and my sister who is also doing M.Sc. in same field from same university. both of us want to do summer project in may-june 2009 from your reputed institution. so kindly send me the full information about it as soon as possible to tyagisandhya@yahoo.com
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