Finding a chance to write on the blog of BII is a subject of honor for me. I am just trying to make reader familiar with the world of Biotechnology/life sciences and there relation with Pharmacology, Here I am trying to set some epic of DNA which is most fascinating thing in health care system as per my view. After the discovery of nuclein (nucleic acid) by Johannes Friedrich Miescher in 1869 which is one of most remarkable work in the world of Life Sciences. It initiate a new era in Life sciences especially in molecular biology. In the initial of 20th century when protein is regarded as the most complex structure as well as genetic material, DNA comes as a medicine. Structure of DNA reveals how the characters are transferred from parents to offspring and transcript the information from genotype to phenotype via RNA and Protein. Writing anything is looks less as per broad view of DNA but 5’ to 3’ end always attract me so I will try my level best to sum-up maximum stuff about DNA and its relation with pharmaceutical industry in my this and upcoming next blogs.
Structure of DNA is very important because it is the key role for remedy of viral, bacterial and mutational problems. As its chemical structure elaborate with addition of pentose sugar purine, pyrimidine and tri phosphate molecule. Where sugar molecule deoxygenate at 2’ no of carbon while Nitrogenous bases are at 1’, when we talk about phosphate structure its added at 5’.That whole compound is regarded as nucleotide, and every new nucleotide join at 3’ end and constitute a new DNA.
Source: Mr. Gourav Kumar
Faculty:Bioinformatics Institute of India
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