Gentel Launches Detection Kit for Ultra-sensitive Chromogenic Detection of Protein
Microarrays

Gentel Biosciences, announced the availability of the APiX ViewTM Detection Kits for ultra- sensitive chromogenic detection of protein bmicroarrays, including reverse phase protein such as SomaPlexTM arrays from Protein Biotechnologies.

APiX chromogenic technology allows for the detection of any biotinylated molecule, generating light grey-to-black spots that are visible to the naked eye and can be scanned with the Gentel Proteomics Multi-System. APiX is also compatible with a variety of secondary antibodies such as anti-mouse anti-rabit. APiX uses a proprietary gold-catalyzed silver deposition and typically achieves measurably improved sensitivity compared to fluorescence
detection.

Phillip Schwartz, President and CEO of Protein biotechnologies recognized the potential of the Gentel reagent and systen for use with Protein Biotechnologies SomaPlexTM tumor lysate arrays. "Our customers are looking for a simple, sensitive, and affordable detection methods for use with SomaPlexTM arrays. The Gentel Prteomics Multisystem meets this need," stated Schwartz. "We are excited about how Gentel's easy-to-use kits and affordable
system can help make arrays accessible to whole a new group of users."

Tumor lysates arrays are a type of reverse phase protein microarray that contains a collection of up to several hundred tumor samples on slide. Antibodies or other probes are applied to the array to detect the abundance of specific protein biomarkers and rapidly measure expression across a large population of tumor samples. Array results are then compared to demographic and relevant clinical disease-specific data on the tumor collection to draw a conclusion. APiX bView detection reagents are compatible with the Gentel Proteomics Multi-System, which provides "scan-to-analysis" functionality for multiplex immunoassays, tumor lysates and antigen arrays as well as Western Blot, ELISA and tissue imaging.